Big Brothers Big Sisters works with the following community partners to enhance our services in Eastern Missouri:
- ARCHS
- City of St. Louis Community Development Administration
- Women on Mission
- St. Louis Mental Health Board
- Cape Girardeau Community Caring Council
- St. Charles County Community Assistance Board
- St. Louis Cardinals
- Science Center
- Pulitzer Foundation
- Portfolio Art Gallery
- Hollyberry Baking Company
- Cape Girardeau Public Schools
- St. Louis Public Schools
- Associated General Contractors
- HealthCare USA
- Human Development Corporation
- United Way of Greater St. Louis
- United Way of Southeast Missouri
- Foxy 95.5
- Hot 104.1
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